Dioxane

Dioxane

SCHEMBL28294558

C1CCOC1.C1COCCO1.CC(C)=O.CC(C)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
PKM P14618 1/20 0.42
PIK3CD O00329 1/20 0.34
GAA P10253 2/20 0.32
LMNA P02545 2/20 0.32
TTR P02766 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TP53 P04637 2/20 0.30
TSHR P16473 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28299228 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2PKMPIK3CDLMNA
Dioxane SCHEMBL10806051 0.89 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMGAALMNA
Tetrahydrofuran SCHEMBL165529 0.86
Tetrahydrofuran SCHEMBL154168 0.86
Isopropyl Alcohol SCHEMBL9004332 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMLMNATTR
Tetrahydrofuran SCHEMBL16738662 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMLMNATTR
Tetrahydrofuran SCHEMBL2143001 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMLMNATTR
Tetrahydrofuran SCHEMBL10806048 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMPIK3CDGAA
Tetrahydrofuran SCHEMBL11690381 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMPIK3CDGAA
Tetrahydrofuran SCHEMBL6927933 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2PKMPIK3CDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109718869-A Ion exchange resin, purification process and the method for preparing ion exchange resin 罗门哈斯电子材料有限责任公司 2019-05-07 CN disclosed