1,4-Butanediol

1,4-Butanediol

SCHEMBL28294560

CC(C)S(=O)(=O)O.OCCCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 2/20 0.36
ATR Q13535 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CA2 P00918 2/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL7623431 1.00 GRIA1 (0.40) GRIA1SMN1; SMN2LMNAALDH1A1TSHR
SCHEMBL5354 0.83
Monoethanolamine SCHEMBL28988166 0.82 TSHR (0.44) GRIA1LMNAALDH1A1TSHRTP53
1,4-Butanediol SCHEMBL28702623 0.80 TP53 (0.38) GRIA1SMN1; SMN2LMNAALDH1A1TSHR
1,4-Butanediol SCHEMBL130918 0.80 SMN1; SMN2 (0.44) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
1,4-Butanediol SCHEMBL15301979 0.80 SMN1; SMN2 (0.44) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
Fluoride SCHEMBL11339901 0.79
Hydrochloric Acid SCHEMBL2671055 0.79
1,4-Butanediol SCHEMBL924158 0.79 CA5A (0.50) SMN1; SMN2LMNAALDH1A1TSHRHSD17B10
SCHEMBL7608901 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776779-A A kind of degradable macromolecular dyestuff of water solubility and preparation method thereof 安徽清彩科技有限公司 2019-05-21 CN disclosed