Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275812 | 0.83 | KMT2A (0.72) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL3609938 | 0.82 | KDM4E (0.60) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL10393959 | 0.81 | KMT2A (0.64) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL3068474 | 0.80 | KMT2A (0.71) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL3068471 | 0.80 | KMT2A (0.71) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL11854131 | 0.80 | TAS2R38 (0.61) | KMT2AGAAALDH1A1MAPK1MAPT | |
| SCHEMBL357522 | 0.80 | KDM4E (0.69) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL3609936 | 0.80 | KDM4E (0.63) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL4500674 | 0.80 | KDM4E (0.58) | KMT2AGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL260429 | 0.80 | KDM4E (0.71) | KMT2AGAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796387-A | The preparation method of thio trifluoroacetyl amine compounds | 温州大学 | 2019-05-24 | — | — | CN | disclosed |