Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL28294690 | 0.98 | MGAM (0.48) | MGAMGAASIMGAM2TLR8 | |
| SCHEMBL8417989 | 0.81 | HSD17B1 (0.43) | MGAMGAASIMGAM2TLR8 | |
| SCHEMBL16195323 | 0.79 | HSD17B1 (0.44) | TLR8HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL28767349 | 0.78 | TLR8 (0.58) | TLR8HSD17B1HSD17B2ESR2ESR1 | |
| Ethane SCHEMBL27714634 | 0.76 | TLR8 (0.59) | GAATLR8HSD17B1HSD17B2ESR2 | |
| SCHEMBL2031812 | 0.75 | TLR8 (0.55) | TLR8HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL6699314 | 0.73 | HSD17B1 (0.53) | TLR8HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL20056693 | 0.72 | HSD17B1 (0.48) | TLR8HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL23496933 | 0.72 | TLR8 (0.52) | TLR8HSD17B1HSD17B2ESR2FYN | |
| SCHEMBL30719599 | 0.72 | TLR8 (0.52) | TLR8HSD17B1HSD17B2ESR2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106916180-B | Polyphenol compound, Preparation method and use | 广东生益科技股份有限公司 | 2019-04-30 | — | — | CN | claimed |