Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651158 | 0.85 | TSHR (0.51) | TSHRTHRBZDHHC7FDPSALDH1A1 | |
| SCHEMBL28204135 | 0.83 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3717075 | 0.83 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3694457 | 0.83 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22318914 | 0.83 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28240290 | 0.82 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28384552 | 0.82 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28330018 | 0.82 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| Bromide SCHEMBL28903015 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8169202 | 0.81 | TSHR (0.80) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880671-A | A kind of high viscosity index improver and its preparation method and application | 一汽解放汽车有限公司 | 2019-06-14 | — | — | CN | disclosed |