Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3698125 | 1.00 | TSHR (0.56) | TSHRTHRBFDPSZDHHC7FAAH | |
| SCHEMBL3694457 | 0.99 | TSHR (0.58) | TSHRTHRBFDPSZDHHC7FAAH | |
| SCHEMBL22318914 | 0.99 | TSHR (0.58) | TSHRTHRBFDPSZDHHC7FAAH | |
| Hydrochloric Acid SCHEMBL10883860 | 0.97 | TSHR (0.56) | TSHRTHRBFDPSZDHHC7FAAH | |
| SCHEMBL1491880 | 0.97 | TSHR (0.55) | TSHRTHRBFDPSZDHHC7FAAH | |
| SCHEMBL11097569 | 0.88 | TSHR (0.58) | TSHRTHRBFDPSZDHHC7FAAH | |
| SCHEMBL16408811 | 0.87 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| Bromide SCHEMBL10881954 | 0.84 | THRB (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10883886 | 0.83 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28294714 | 0.82 | TSHR (0.66) | TSHRTHRBFDPSZDHHC7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403693-A | Integrated biological composite emulsion and preparation method thereof | 四川申和新材料科技有限公司 | 2022-11-29 | — | — | CN | disclosed |