Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294733 | 0.83 | HDAC1 (0.53) | NR1H4HDAC8HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL14927309 | 0.80 | HDAC8 (0.55) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL13698098 | 0.80 | ACHE (0.60) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL11630586 | 0.79 | ACHE (0.55) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL4315070 | 0.78 | ALDH1A1 (0.61) | HDAC8HDAC6KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13155121 | 0.77 | ALDH1A1 (0.57) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL10120025 | 0.75 | HDAC8 (0.59) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL12201883 | 0.75 | HDAC8 (0.77) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL7218374 | 0.75 | ACHE (0.72) | ACHENR1H4HDAC8HDAC6KMT2A | |
| SCHEMBL15317677 | 0.74 | NPSR1 (0.74) | ACHENR1H4HDAC8HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593225-B | novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2019-04-16 | — | — | CN | disclosed |