Sulfuric Acid

Sulfuric Acid

SCHEMBL28294778

CCCc1ccc2ccccc2n1.O=S(=O)(O)O

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 1/20 0.48
PDE10A Q9Y233 5/20 0.47
GPBAR1 Q8TDU6 3/20 0.43
CYSLTR1 Q9Y271 3/20 0.43
CYSLTR2 Q9NS75 2/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725176 0.89 PDE10A (0.54) CYP1A2KDM4EPDE10AGPBAR1CYSLTR1
Iodide SCHEMBL1343671 0.88 PDE10A (0.53) CYP1A2KDM4EPDE10AGPBAR1CYSLTR1
SCHEMBL29047068 0.88 PDE10A (0.53) CYP1A2KDM4EPDE10AGPBAR1CYSLTR1
SCHEMBL28437259 0.86 KDM4E (0.50) CYP1A2KDM4EPDE10AMEN1GAA
SCHEMBL6367036 0.86 KDM4E (0.50) CYP1A2KDM4EPDE10AMEN1GAA
SCHEMBL28709736 0.83 PDE10A (0.49) CYP1A2KDM4EPDE10AGPBAR1CYSLTR1
SCHEMBL10910525 0.83 GPBAR1 (0.51) CYP1A2PDE10AGPBAR1CYSLTR1CYSLTR2
Sulfuric Acid SCHEMBL28670154 0.82 CYP1A2 (0.45) CYP1A2PDE10AGPBAR1CYSLTR1CYSLTR2
Sulfuric Acid SCHEMBL3119154 0.81 CYSLTR1 (0.50) CYP1A2PDE10AGPBAR1CYSLTR1CYSLTR2
SCHEMBL4376467 0.79 CYP1A2 (0.51) CYP1A2PDE10AGPBAR1CYSLTR1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109722282-B Method for preparing alkylate 中国石油化工股份有限公司 2021-05-14 CN disclosed
CN-109722282-A A method of preparing alkylate oil 中国石油化工股份有限公司 2019-05-07 CN disclosed