Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1343671 | 0.98 | PDE10A (0.53) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL29047068 | 0.98 | PDE10A (0.53) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL10910525 | 0.93 | GPBAR1 (0.51) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL28709736 | 0.93 | PDE10A (0.49) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| Sulfuric Acid SCHEMBL28294778 | 0.89 | CYP1A2 (0.50) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL538491 | 0.88 | GPBAR1 (0.54) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| SCHEMBL2913941 | 0.87 | PDE10A (0.61) | PDE10ACYSLTR1CYSLTR2CYP1A2 | |
| SCHEMBL860157 | 0.86 | KCNH2 (0.58) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| Hydrochloric Acid SCHEMBL27600363 | 0.86 | GPBAR1 (0.52) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 | |
| Bromide SCHEMBL27600369 | 0.86 | GPBAR1 (0.52) | PDE10ACYSLTR1GPBAR1CYSLTR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118102874-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-116634874-A | Fungicidal oxadiazoles and mixtures thereof | FMC公司 | 2023-08-22 | — | — | CN | claimed |
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | claimed |
| CN-113980583-A | Ultraviolet curing composition glue based on pyridine substituted acrylate compound and using method and application thereof | 西安思摩威新材料有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110128371-A | A kind of phenthazine benzaldehyde derivative and preparation method thereof, phenthazine quinoline fluorescence probe and its preparation method and application | 中国科学院上海微系统与信息技术研究所 | 2019-08-16 | — | — | CN | claimed |
| CN-109678797-A | A method of quickly preparing ABA Receptor agonist | 邵阳学院 | 2019-04-26 | — | — | CN | claimed |
| CN-109111399-A | Novel human-derived γ-aminobutyric acid A receptor agonist and preparation method thereof | 宁波市农业科学研究院 | 2019-01-01 | — | — | CN | claimed |
| EP-2608792-B1 | METHODS OF ADMINISTERING AN EGFR INHIBITOR | BOEHRINGER INGELHEIM INT (DE) | 2017-10-11 | — | — | EP | claimed |
| US-20160287591-A1 | METHODS OF ADMINISTERING AN EGFR INHIBITOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-10-06 | — | — | US | claimed |
| EP-2188259-B1 | QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | UNIV HONG KONG POLYTECHNIC (CN) | 2013-11-06 | — | — | EP | claimed |
| US-8344145-B2 | Salts of 2-substituted quinolines | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2013-01-01 | — | — | US | claimed |
| US-20110144154-A1 | Salts of 2-Substituted Quinolines | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2011-06-16 | — | — | US | claimed |
| EP-2271343-A1 | SALTS OF 2-SUBSTITUTED QUINOLINES | Institut de Recherche pour le Développement (FR) | 2011-01-12 | — | — | EP | claimed |
| WO-2009144407-A1 | SALTS OF 2-SUBSTITUTED QUINOLINES | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2009-12-03 | — | — | WO | claimed |
| WO-2009024095-A1 | METHOD OF MAKING AND ADMINISTERING QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-02-26 | — | — | WO | claimed |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-02-26 | — | — | US | claimed |
| WO-2005028452-A9 | SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LTD (GB) | 2005-07-21 | — | — | WO | claimed |
| WO-2002098966-A2 | AROMATIC PRINCIPLES FOR IMPROVING THE STABILITY IN STORAGE AND/OR FOR IMPROVING THE SOLUBILITY OF POLYVINYL ALCOHOLS AND/OR POLYVINYL ALCOHOLS WITH BONDED CELLULOSE | DROM FRAGRANCES INTERNATIONAL KG (DE) | 2002-12-12 | — | — | WO | claimed |
| US-5541196-A | ANTIPROTOZOA AGENTS | INSTITUT FRANCAIS DE RECHERCHE SCIENTIFIQUE POUR LE DEVELOPPMENT EN COOPERATION (ORSTOM) (FR) | 1996-07-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287591-A1 | METHODS OF ADMINISTERING AN EGFR INHIBITOR | EGFR, ERBB2, ERBB3 | PDE10A 3400/4885CYSLTR1 2384/4885GPBAR1 38/4885 |
| US-20090054482-A1 | Method of making and administering quinoline derivatives as anti-cancer agents | HCCS, GLS2, NQO1 | PDE10A 4283/4885CYSLTR1 4159/4885GPBAR1 1506/4885 |
| US-20110144154-A1 | Salts of 2-Substituted Quinolines | NQO2, SULT2A1, QTRT2 | PDE10A 729/4885CYSLTR1 4176/4885GPBAR1 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.