Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2279356 | 0.94 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBFDPSALPL | |
| SCHEMBL486434 | 0.89 | — | — | |
| Pivalate SCHEMBL25287363 | 0.89 | FDPS (0.47) | ALDH1A1KMT2APOLBFDPSALPL | |
| Trifluoroacetic Acid SCHEMBL15377959 | 0.89 | FDPS (0.47) | ALDH1A1KMT2APOLBFDPSALPL | |
| SCHEMBL21331986 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBFDPSALPL | |
| Bromide SCHEMBL1237833 | 0.87 | — | — | |
| Hydrogen Sulfide SCHEMBL28101812 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1202962 | 0.87 | — | — | |
| Iodide SCHEMBL4268734 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL28650399 | 0.86 | KMT2A (0.52) | ALDH1A1KMT2APOLBFDPSALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836849-B | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-109790292-B | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-111836849-A | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-109790292-A | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2019-05-21 | — | — | CN | disclosed |