Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147539 | 0.88 | SRD5A2 (0.61) | SRD5A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10991966 | 0.88 | PARP10 (0.51) | SRD5A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3128289 | 0.88 | SRD5A2 (0.61) | SRD5A2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11508522 | 0.86 | MAPT (0.63) | MEN1ALDH1A1HPGDKMT2APARP10 | |
| SCHEMBL3022624 | 0.86 | PARP10 (0.73) | ALDH1A1KMT2APARP10PARP14TNKS | |
| SCHEMBL6290496 | 0.84 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AMGLLKCNH2 | |
| SCHEMBL6289347 | 0.84 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AMGLLKCNH2 | |
| SCHEMBL9937559 | 0.83 | RAB9A (0.57) | MEN1ALDH1A1HPGDKMT2APARP10 | |
| SCHEMBL6290588 | 0.82 | SMN1; SMN2 (0.58) | MEN1ALDH1A1KMT2AMGLLKCNH2 | |
| SCHEMBL6290729 | 0.82 | SMN1; SMN2 (0.58) | MEN1ALDH1A1KMT2AMGLLKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |