Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151194 | 0.84 | MAPT (0.50) | MAPTPOLBCDK8ACVR1NPC1 | |
| SCHEMBL1726326 | 0.83 | MAPT (0.59) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL1725607 | 0.81 | MAPT (0.49) | MAPTPOLBMAPK14KDM4EALDH1A1 | |
| SCHEMBL28195585 | 0.80 | MAPT (0.60) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL28298139 | 0.80 | MAPT (0.60) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL2579633 | 0.80 | MAPT (0.51) | MAPTPOLBCDK8SMN1; SMN2NPC1 | |
| SCHEMBL16402315 | 0.78 | MAPT (0.46) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL19743580 | 0.76 | MAPT (0.51) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL29039033 | 0.76 | MAPT (0.51) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL4219600 | 0.75 | MAPT (1.00) | MAPTPOLBCDK8ACVR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890206-A | Anil that 4- is substituted and its plant pathogenic microorganisms being not intended in confrontation are with the purposes on cover crop | 印度商皮埃企业有限公司 | 2019-06-14 | — | — | CN | disclosed |