Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039033 | 0.89 | MAPT (0.51) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL19743580 | 0.89 | MAPT (0.51) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL28294976 | 0.83 | MAPT (0.60) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL27207771 | 0.83 | PKM (0.47) | MAPTCDK8ACVR1SMN1; SMN2NPC1 | |
| SCHEMBL15639816 | 0.81 | BRD4 (0.45) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL29097494 | 0.81 | MAPT (0.50) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL30151194 | 0.81 | MAPT (0.50) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL1725188 | 0.81 | MAPT (0.49) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL15952575 | 0.79 | MAPT (0.39) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL1726309 | 0.79 | MAPT (0.39) | MAPTCDK8ACVR1SMN1; SMN2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | claimed |
| US-20140235689-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-21 | — | — | US | disclosed |
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235689-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, NOX3 | MAPT 3557/4885POLB 3197/4885CDK8 2357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.