Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726326 | 0.89 | MAPT (0.59) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL29039033 | 0.82 | MAPT (0.51) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL28195585 | 0.76 | MAPT (0.60) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL28294976 | 0.76 | MAPT (0.60) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL27207771 | 0.76 | PKM (0.47) | MAPTCDK8ACVR1SMN1; SMN2NPC1 | |
| SCHEMBL15952575 | 0.76 | MAPT (0.39) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL29097494 | 0.75 | MAPT (0.50) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL30151194 | 0.75 | MAPT (0.50) | MAPTPOLBCDK8ACVR1MAPK14 | |
| SCHEMBL15639816 | 0.72 | BRD4 (0.45) | MAPTPOLBCDK8ACVR1SMN1; SMN2 | |
| SCHEMBL30415275 | 0.72 | MAPT (0.46) | MAPTPOLBCDK8ACVR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118102874-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116234444-A | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | 皮埃企业有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-118102874-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116234444-A | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | 皮埃企业有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-3601279-A1 | TRICYCLIC CARBOXAMIDES FOR CONTROLLING ARTHROPODS | Bayer CropScience Aktiengesellschaft (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2017220491-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-28 | — | — | WO | disclosed |