Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397079 | 0.89 | POLB (0.61) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL9458638 | 0.88 | SRD5A2 (0.54) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL28533938 | 0.86 | SRD5A2 (0.52) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL27486214 | 0.86 | PARP10 (0.61) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL19041838 | 0.85 | XDH (0.52) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL522526 | 0.82 | PTGS2 (0.55) | SRD5A2POLBCYP2C9CYP2C19HPGD | |
| SCHEMBL9457798 | 0.82 | SRD5A2 (0.52) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL19533552 | 0.82 | SRD5A2 (0.49) | SRD5A2POLBNR1H4BCL2MCL1 | |
| SCHEMBL14966709 | 0.81 | SRD5A2 (0.48) | SRD5A2POLBNR1H4PARP10AKR1C3 | |
| SCHEMBL7623240 | 0.81 | POLB (0.54) | SRD5A2POLBNR1H4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |