Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902294 | 0.84 | MEN1 (0.47) | ESR1ESR2GPR84MEN1KMT2A | |
| SCHEMBL272956 | 0.84 | MEN1 (0.47) | ESR1ESR2GPR84MEN1KMT2A | |
| Water SCHEMBL10783729 | 0.82 | KMT2A (0.46) | ESR1ESR2GPR84MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL29267919 | 0.82 | MEN1 (0.46) | ESR1ESR2GPR84MEN1KMT2A | |
| SCHEMBL1274371 | 0.81 | ESR1 (0.42) | ESR1ESR2GPR84CYP3A4MEN1 | |
| SCHEMBL21461867 | 0.80 | BACE1 (0.44) | ESR1ESR2BACE1JAK2CYP3A4 | |
| SCHEMBL7652128 | 0.75 | MEN1 (0.51) | GPR84CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL1274355 | 0.75 | HPRT1 (0.49) | ESR1ESR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1456297 | 0.75 | GRM2 (0.41) | GPR84CYP3A4CYP1A2CYP2C19MEN1 | |
| SCHEMBL29803814 | 0.73 | CYP1A1 (0.45) | ESR1ESR2BACE1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790457-A | Aromatic amine derivant and its preparation method and application | 广州华睿光电材料有限公司 | 2019-05-21 | — | — | CN | disclosed |