SCHEMBL272956

SCHEMBL272956

Nc1c(-c2ccccc2)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
RECQL P46063 1/20 0.47
KDM4E B2RXH2 5/20 0.47
MAPT P10636 3/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
MPI P34949 1/20 0.47
GPR84 Q9NQS5 6/20 0.46
ALOX5 P09917 1/20 0.45
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
CYP11B1 P15538 1/20 0.40
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30902294 1.00 MEN1 (0.47) MEN1KMT2ARECQLKDM4EMAPT
Ammonia Solution, Strong SCHEMBL29267919 0.98 MEN1 (0.46) MEN1KMT2ARECQLKDM4EMAPT
Water SCHEMBL10783729 0.98 KMT2A (0.46) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL7652128 0.86 MEN1 (0.51) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL1456297 0.86 GRM2 (0.41) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL1274371 0.85 ESR1 (0.42) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL16860069 0.85 GPR84 (0.50) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL16110931 0.84 MEN1 (0.42) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL1767908 0.84 ALDH1A1 (0.50) MEN1KMT2ARECQLKDM4EMAPT
SCHEMBL28295001 0.84 ESR1 (0.44) MEN1KMT2ARECQLKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722288-B2 Diphenylnaphthylamine derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2014-05-13 US claimed
EP-2497764-A1 DIPHENYLNAPHTHYLAMINE DERIVATIVE Hodogaya Chemical Co., Ltd. (JP) 2012-09-12 EP claimed
US-20120208117-A1 DIPHENYLNAPHTHYLAMINE DERIVATIVES HODOGAYA CHEMICAL CO., LTD. (JP) 2012-08-16 US claimed
US-6630254-B2 Comprising poly(N-octyl-2,7-carbazole); for use in electronics/electrooptics NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-10-07 US claimed
US-20030008172-A1 Conjugated polycarbazole derivatives in Organic Light Emitting Diodes NATIONAL RESEARCH COUNCIL (CA) 2003-01-09 US claimed
US-6326122-B1 HEAT SENSITIVE ELEMENTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-12-04 US claimed
JP-5059169-A None JP disclosed
EP-3957494-B1 RUBBER REINFORCEMENT ADHESIVE GOODYEAR TIRE & RUBBER (US) 2025-02-19 EP disclosed
US-20250042201-A1 NON-PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2025-02-06 US disclosed
EP-4501663-A1 NON-PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2025-02-05 EP disclosed
CN-111324008-B Photosensitive composition and application thereof 乐凯华光印刷科技有限公司 2023-04-14 CN disclosed
CN-115443278-A Heterocyclic compound and organic light-emitting device including same LT素材株式会社 2022-12-06 CN disclosed
EP-4008567-A1 TIRE WITH ETHYLENE-VINYL ALCOHOL COPOLYMER INNERLINER The Goodyear Tire & Rubber Company (US) 2022-06-08 EP disclosed
EP-0823327-A2 Positive photosensitive composition, positive photosensitive lithographic printing plate and method for making positive photosensitive lithographic printing plate Mitsubishi Chemical Corporation (JP) 1998-02-11 EP disclosed
JP-H0559169-A POLYIMIDE RESIN IMAI YOSHIO 1993-03-09 JP disclosed
US-5151142-A Fatigue resistance BRIDGESTONE CORPORATION (JP) 1992-09-29 US disclosed
EP-0162313-B1 PROCESS FOR THE PRODUCTION OF RUBBERREINFORCING POLYESTER CORD Toyo Boseki Kabushiki Kaisha (JP) 1991-08-07 EP disclosed
US-4720398-A Process for the improvement of the adhesion to rubber or a thermoplastic elastomer of synthetic yarns, cords or fabrics made therefrom AKZO NV (NL) 1988-01-19 US disclosed
EP-0168066-A1 Process for the improvement of the adhesion to rubber or a thermoplastic elastomer of synthetic yarns, cords or fabrics made therefrom AKZO N.V. (NL) 1986-01-15 EP disclosed
EP-0162313-A2 Process for the production of rubberreinforcing polyester cord Toyo Boseki Kabushiki Kaisha (JP) 1985-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208117-A1 DIPHENYLNAPHTHYLAMINE DERIVATIVES SLC19A1, SLC29A1, SLCO2A1 MEN1 3389/4885KMT2A 2729/4885RECQL 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.