SCHEMBL7652128

SCHEMBL7652128

Cc1ccc(-c2cc3ccccc3c(N)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
GPR84 Q9NQS5 2/20 0.50
ADORA2A P29274 2/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 2/20 0.40
HPGD P15428 2/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2A6 P11509 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ENPP1 P22413 1/20 0.38
ADORA1 P30542 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5461463 0.86 MEN1 (0.54) MEN1KMT2ANPC1RAB9AGPR84
SCHEMBL30902294 0.86 MEN1 (0.47) MEN1KMT2AGPR84KDM4EALDH1A1
SCHEMBL272956 0.86 MEN1 (0.47) MEN1KMT2AGPR84KDM4EALDH1A1
Water SCHEMBL10783729 0.84 KMT2A (0.46) MEN1KMT2ARAB9AGPR84KDM4E
Ammonia Solution, Strong SCHEMBL29267919 0.84 MEN1 (0.46) MEN1KMT2AGPR84KDM4EALDH1A1
SCHEMBL1456297 0.83 GRM2 (0.41) MEN1KMT2ANPC1RAB9AGPR84
SCHEMBL22664756 0.80 GPR84 (0.40) MEN1KMT2ANPC1RAB9AGPR84
SCHEMBL7620992 0.79 GPR84 (0.37) MEN1KMT2ANPC1RAB9AGPR84
SCHEMBL17559483 0.77 NPC1 (0.47) MEN1KMT2ANPC1RAB9AGPR84
SCHEMBL24174147 0.77 GPR84 (0.53) MEN1KMT2ANPC1RAB9AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6492079-B2 CHARGE TRANSFER COMPOUND; CHARGE GENERATING COMPOUND ON ELECTROCONDUCTIVE SUPPORT RICOH COMPANY, LTD. (JP) 2002-12-10 US disclosed
US-20020028400-A1 Electrophotographic photoconductor, image forming apparatus, and process cartridge using the photoconductor RICOH COMPANY, LTD. (JP) 2002-03-07 US disclosed