SCHEMBL28295005

SCHEMBL28295005

Cc1cc(N)c(Cl)cc1N(c1ccccc1)S(C)(=O)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
GAA P10253 1/20 0.33
CD44 P16070 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26908434 0.87 TSHR (0.35) CYP3A4LMNAPOLBALDH1A1GAA
SCHEMBL26908437 0.77 MAPK13 (0.42) SMN1; SMN2KDM4ELMNAPOLBALDH1A1
SCHEMBL21495770 0.76 KMT2A (0.34) SMN1; SMN2KDM4ELMNAPOLBKMT2A
SCHEMBL27792301 0.75 PKM (0.39) CYP2C9ALDH1A1GAAKMT2AESR1
SCHEMBL28296744 0.72 PKM (0.37) CYP3A4LMNAPOLBALDH1A1CYP1A1
SCHEMBL1704542 0.70 PKM (0.50) ALDH1A1MEN1KMT2AESR1
SCHEMBL5928486 0.70 NSD2 (0.51) SMN1; SMN2LMNAPOLBALDH1A1GAA
SCHEMBL5928309 0.69 KMT2A (0.48) SMN1; SMN2KDM4EPOLBALDH1A1GAA
SCHEMBL529036 0.68 NPSR1 (0.41) SMN1; SMN2LMNAPOLBGAAMEN1
SCHEMBL30641714 0.68 MAPK13 (0.40) SMN1; SMN2LMNAPOLBALDH1A1MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890206-A Anil that 4- is substituted and its plant pathogenic microorganisms being not intended in confrontation are with the purposes on cover crop 印度商皮埃企业有限公司 2019-06-14 CN disclosed