Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528892 | 0.82 | MAPT (0.41) | NPSR1MAPTSMN1; SMN2POLBESR1 | |
| SCHEMBL12505329 | 0.80 | MAPT (0.44) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL528821 | 0.79 | L3MBTL1 (0.44) | NPSR1MAPTSMN1; SMN2POLBESR1 | |
| SCHEMBL528635 | 0.79 | ALDH1A1 (0.43) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL529539 | 0.76 | MAPT (0.44) | NPSR1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL5928299 | 0.74 | KDM4E (0.47) | SMN1; SMN2POLBRAB9ALMNAMEN1 | |
| SCHEMBL21101926 | 0.69 | LMNA (0.42) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL528260 | 0.69 | ALDH1A1 (0.39) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL529554 | 0.69 | ALDH1A1 (0.46) | NPSR1MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL28295005 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2POLBRAB9AESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |