Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.64 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | P4HB | P07237 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296782 | 1.00 | CTSL (0.64) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL15679324 | 0.88 | CTSL (0.67) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL24178475 | 0.88 | CTSL (0.67) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL15678377 | 0.86 | CTSL (0.64) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL31327535 | 0.85 | CTSL (0.61) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL4782666 | 0.85 | CTSL (0.63) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL6409052 | 0.85 | CTSL (0.63) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL850438 | 0.85 | ACE (0.77) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL3560147 | 0.85 | CTSL (0.63) | CTSLCTSSCTSKTACR1MAPT | |
| SCHEMBL23126843 | 0.85 | CTSL (0.63) | CTSLCTSSCTSKTACR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | claimed |