Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.77 |
| ▸ | CTSL | P07711 | 2/20 | 0.76 |
| ▸ | CTSS | P25774 | 1/20 | 0.76 |
| ▸ | CTSK | P43235 | 1/20 | 0.76 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.70 |
| ▸ | TACR1 | P25103 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.62 |
| ▸ | ITGAL | P20701 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003555 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL29367687 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL1486167 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30976323 | 1.00 | ACE (0.77) | ACECTSLCTSSCTSKSCN9A | |
| Hydrochloric Acid SCHEMBL31472643 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL30699849 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| Fluoride SCHEMBL7445962 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| Fluoride SCHEMBL7445954 | 0.99 | ACE (0.75) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL11403615 | 0.96 | ACE (0.84) | ACECTSLCTSSCTSKSCN9A | |
| SCHEMBL27871524 | 0.96 | CTSL (0.76) | ACECTSLCTSSCTSKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724780-B | Acylthiourea compound based on hydrophobic tag, preparation method thereof and application of acylthiourea compound in resisting influenza A virus | 武汉大学 | 2024-04-26 | — | — | CN | claimed |
| CN-115724780-A | Acyl thiourea compound based on hydrophobic label, preparation method thereof and application of acyl thiourea compound in resisting influenza A virus | 武汉大学 | 2023-03-03 | — | — | CN | claimed |
| CN-112538040-A | Preparation method of tryptophan oxide | 艾希尔（深圳）药物研发有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-106967151-B | Multi-site combination modified endomorphin analogue and synthesis and application thereof | 兰州大学 | 2020-08-11 | — | — | CN | claimed |
| US-10000520-B2 | B-vitamin and amino acid conjugates ofnicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof | ChromaDex Inc. (US) | 2018-06-19 | — | — | US | claimed |
| US-20170267709-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OFNICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | ChromaDex Inc. (US) | 2017-09-21 | — | — | US | claimed |
| CN-104877005-A | Non-natural amino acid modified endomorphin-1 analogue as well as synthesis method and application thereof | UNIV LANZHOU | 2015-09-02 | — | — | CN | claimed |
| CN-103214552-B | Synthesis and application of multi-site modified endomorphin-1 analogue | UNIV LANZHOU | 2015-01-21 | — | — | CN | claimed |
| CN-103214552-A | Synthesis and application of multi-site modified endomorphin-1 analogue | UNIV LANGZHOU | 2013-07-24 | — | — | CN | claimed |
| CN-102558297-B | Endomorphin-1 analogue modified by alpha-alkenyl-beta-amino acid and composition and application thereof | UNIV LANGZHOU | 2013-07-17 | — | — | CN | claimed |
| CN-102558297-A | Endomorphin-1 analogue modified by alpha-alkenyl-beta-amino acid and composition and application thereof | UNIV LANGZHOU | 2012-07-11 | — | — | CN | claimed |
| EP-3894390-B1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | HEIDELBERG PHARMA RES GMBH (DE) | 2026-05-20 | — | — | EP | disclosed |
| US-12625431-B2 | EUV resist underlayer film-forming composition | NISSAN CHEMICAL CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12378196-B2 | Synthesis of (S)-6-hydroxytryptophan and derivatives thereof | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-08-05 | — | — | US | disclosed |
| US-20250179018-A1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| CN-1049155-A | INDOLE DERIVATIVES | OTSUKA CHEMICAL CO LTD (JP) | 1991-02-13 | — | — | CN | disclosed |
| US-4724237-A | GASTROINTESTINAL, CENTRAL NERVOUS, AND APPETITE DISORDERS | MERCK & CO., INC. (US) | 1988-02-09 | — | — | US | disclosed |
| EP-0166356-A2 | 2-Substituted-aminomethyl-1,4-benzodiazepines, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4554272-A | CHOLECYSTOKININ INHIBITORS | MERCK & CO., INC. (US) | 1985-11-19 | — | — | US | disclosed |
| US-3974135-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same | FOLKERS KARL | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000520-B2 | B-vitamin and amino acid conjugates ofnicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof | NAMPT, NAPRT, NNMT | ACE 4681/4885CTSL 4053/4885CTSS 4478/4885 |
| US-12625431-B2 | EUV resist underlayer film-forming composition | EEF1A1, ARF1, EMG1 | ACE 4356/4885CTSL 4383/4885CTSS 4528/4885 |
| US-20250179018-A1 | SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF | AANAT, HNMT, HTR6 | ACE 1490/4885CTSL 776/4885CTSS 846/4885 |
| US-12378196-B2 | Synthesis of (S)-6-hydroxytryptophan and derivatives thereof | AANAT, HNMT, HTR6 | ACE 1271/4885CTSL 878/4885CTSS 832/4885 |
| US-20170267709-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OFNICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | NAMPT, NAPRT, NNMT | ACE 4681/4885CTSL 4053/4885CTSS 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.