Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470174 | 0.94 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL2330762 | 0.94 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15214215 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL13310981 | 0.75 | CYP2D6 (0.71) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3470314 | 0.73 | MEN1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL2330425 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2462678 | 0.72 | MAPT (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL2332426 | 0.72 | MEN1 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2365016 | 0.72 | CYP1A2 (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2333441 | 0.72 | S1PR2 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109674797-B | Application of small molecule as lysyl tRNA synthetase inhibitor | 苏州大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109674797-A | A kind of purposes of the inhibitor of small molecule as lysyl tRNA synzyme | 苏州大学 | 2019-04-26 | — | — | CN | disclosed |