Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28295154

C1CCOC1.CC(C)=O.CCC(C)=O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
TDP1 Q9NUW8 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 2/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 3/20 0.33
POLB P06746 2/20 0.33
PAOX Q6QHF9 1/20 0.33
SLC15A2 Q16348 1/20 0.32
FFAR3 O14843 1/20 0.32
RECQL P46063 1/20 0.31
GLA P06280 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL442775 0.97 ALDH1A1 (0.56) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL28279972 0.97 ALDH1A1 (0.56) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Butanone SCHEMBL2962461 0.95 ALDH1A1 (0.53) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL18862833 0.95 ALDH1A1 (0.53) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL7051923 0.86 ALDH1A1 (0.44) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL28312571 0.86 ALDH1A1 (0.43) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Dioxane SCHEMBL2962462 0.86 ALDH1A1 (0.62) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL165529 0.86
Acetone SCHEMBL15059718 0.84 ALDH1A1 (0.42) ALDH1A1TDP1SMN1; SMN2TSHRHTT
Tetrahydrofuran SCHEMBL27898407 0.84 ALDH1A1 (0.42) ALDH1A1TDP1SMN1; SMN2TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103562-B Thermochemical process for recycling fiberglass reinforced plastic waste 科瑞克公司 2019-06-18 CN claimed