SCHEMBL28295313

SCHEMBL28295313

CN(CCCN=[N+]=[N-])C[C@H](O)COC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GGPS1 O95749 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295317 1.00 CYP1A2 (0.33) CYP1A2KDM4ELMNASMN1; SMN2GGPS1
SCHEMBL28767515 0.81
SCHEMBL28295319 0.79 CYP1A2 (0.40) CYP1A2KDM4ELMNASMN1; SMN2GGPS1
SCHEMBL28295318 0.79 CYP1A2 (0.40) CYP1A2KDM4ELMNASMN1; SMN2GGPS1
SCHEMBL28293537 0.79 CHRNB2 (0.37) LMNA
SCHEMBL29046396 0.76 KDM4E (0.41) CYP1A2KDM4ELMNASMN1; SMN2
SCHEMBL28966725 0.76 KDM4E (0.41) CYP1A2KDM4ELMNASMN1; SMN2
SCHEMBL19834211 0.74 CYP2D6 (0.33)
SCHEMBL19834210 0.74 CYP2D6 (0.33)
SCHEMBL19849085 0.71 MEN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790152-A The diagnosis of neurotensin receptor associated disease treats and prevents 埃朗根-纽伦堡 弗里德里希-亚历山大大学 2019-05-21 CN disclosed