Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18876588 | 0.83 | LMNA (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 | |
| SCHEMBL28990999 | 0.81 | LMNA (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 | |
| SCHEMBL13736933 | 0.80 | PRSS1 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 | |
| SCHEMBL28295317 | 0.79 | CYP1A2 (0.33) | LMNA | |
| SCHEMBL28295313 | 0.79 | CYP1A2 (0.33) | LMNA | |
| SCHEMBL29025239 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3SCN1A | |
| SCHEMBL22291523 | 0.76 | CHRM2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3SCN1A | |
| SCHEMBL28515855 | 0.76 | PRSS1 (0.36) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL15468776 | 0.75 | — | — | |
| SCHEMBL28293534 | 0.75 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790152-A | The diagnosis of neurotensin receptor associated disease treats and prevents | 埃朗根-纽伦堡 弗里德里希-亚历山大大学 | 2019-05-21 | — | — | CN | disclosed |