Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293385 | 0.84 | POLB (0.55) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2514163 | 0.83 | MAPK1 (0.56) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27362726 | 0.81 | SMN1; SMN2 (0.39) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14665755 | 0.81 | GAA (0.57) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18055499 | 0.80 | MAPT (0.64) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31522200 | 0.79 | ALDH1A1 (0.58) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31522201 | 0.79 | ALDH1A1 (0.58) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL405007 | 0.78 | ALDH1A1 (0.71) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28293268 | 0.77 | SMN1; SMN2 (0.43) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL18161149 | 0.75 | GAA (0.58) | GAAMAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651253-A | Cinnamic acid ester derivant and its application as nerve protection medicine | 上海医药工业研究院 | 2019-04-19 | — | — | CN | disclosed |