Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293268 | 0.86 | SMN1; SMN2 (0.43) | POLBSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL28295432 | 0.84 | GAA (0.55) | POLBGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28872888 | 0.83 | KCNJ6 (0.44) | SMN1; SMN2MEN1KMT2APTGS2LMNA | |
| SCHEMBL2514163 | 0.83 | MAPK1 (0.56) | GAASMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL28872885 | 0.81 | LMNA (0.60) | POLBGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28295435 | 0.80 | POLB (0.43) | POLBMEN1KMT2APTGS2HPGD | |
| SCHEMBL27868556 | 0.80 | GAA (0.56) | POLBGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27868554 | 0.78 | MAPT (0.38) | POLBGAASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL27973503 | 0.77 | POLB (0.55) | POLBGAASMN1; SMN2KDM4EALDH1A1 | |
| Phosphine SCHEMBL28064259 | 0.77 | PTGS2 (0.58) | POLBSMN1; SMN2PTGS2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651253-A | Cinnamic acid ester derivant and its application as nerve protection medicine | 上海医药工业研究院 | 2019-04-19 | — | — | CN | disclosed |
| CN-109640934-A | Method of increasing the absorption and washfastness of hair health compounds | 宝洁公司 | 2019-04-16 | — | — | CN | disclosed |