Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297189 | 0.88 | CCKBR (0.60) | CCKBRCHRM1CHRM5 | |
| SCHEMBL28297206 | 0.81 | CCKBR (0.48) | CCKBRCHRM1TRPV1 | |
| Bromide SCHEMBL9526214 | 0.76 | CCKBR (0.59) | CCKBRCHRM1 | |
| Bromide SCHEMBL9526221 | 0.76 | CCKBR (0.59) | CCKBRCHRM1 | |
| SCHEMBL21272067 | 0.76 | CHRM1 (0.56) | CHRM1CHRM5TRPV1 | |
| SCHEMBL28295476 | 0.72 | CHRM1 (0.61) | CHRM1CHRM5TRPV1 | |
| SCHEMBL28297200 | 0.72 | CHRM1 (0.61) | CHRM1CHRM5TRPV1 | |
| SCHEMBL28297188 | 0.72 | CHRM1 (0.49) | CCKBRCHRM1 | |
| SCHEMBL11265240 | 0.71 | GABRA1 (0.52) | CCKBRCHRM1CHRM5TRPV1 | |
| SCHEMBL28297201 | 0.71 | CHRM1 (0.46) | CCKBRCHRM1CHRM5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109906220-A | For treating the 1,3- dihydro -1,4- benzodiazepine * -2- thione compounds of CNS related disease | 豪夫迈·罗氏有限公司 | 2019-06-18 | — | — | CN | claimed |
| CN-109906220-A | For treating the 1,3- dihydro -1,4- benzodiazepine * -2- thione compounds of CNS related disease | 豪夫迈·罗氏有限公司 | 2019-06-18 | — | — | CN | disclosed |