Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355282 | 0.82 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1MAPK8TDP1KMT2A | |
| SCHEMBL30141188 | 0.76 | TSHR (0.57) | ALDH1A1CA1CA2 | |
| SCHEMBL5364748 | 0.74 | HPGD (0.78) | L3MBTL1ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL3561653 | 0.74 | NPC1 (0.75) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29994178 | 0.74 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1MAPK8TDP1KMT2A | |
| SCHEMBL14727425 | 0.74 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1MAPK8TDP1KMT2A | |
| SCHEMBL2305929 | 0.74 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1MAPK8TDP1KMT2A | |
| SCHEMBL6355306 | 0.73 | L3MBTL1 (0.74) | L3MBTL1ALDH1A1MAPK8TDP1NPC1 | |
| SCHEMBL2912570 | 0.73 | SMN1; SMN2 (0.82) | L3MBTL1ALDH1A1MAPK8TDP1KMT2A | |
| SCHEMBL5860823 | 0.73 | NPC1 (0.71) | L3MBTL1ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-A | 2- (2- amino benzoyl) benzoic acid derivative and preparation method thereof | 厦门华厦学院 | 2019-04-19 | — | — | CN | disclosed |