Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295520 | 0.89 | CDC7 (0.64) | CDC7DBF4DHODHLMNAALDH1A1 | |
| SCHEMBL28297249 | 0.85 | CDC7 (0.53) | CDC7DBF4DHODHLMNAALDH1A1 | |
| SCHEMBL289996 | 0.84 | CDC7 (0.65) | CDC7DBF4DHODHLMNAALDH1A1 | |
| SCHEMBL28297251 | 0.84 | MAPT (0.54) | CDC7DBF4LMNAALDH1A1KDM4E | |
| SCHEMBL28295659 | 0.84 | CDC7 (0.57) | CDC7DBF4LMNAALDH1A1KDM4E | |
| SCHEMBL28297235 | 0.83 | CDC7 (0.59) | CDC7DBF4LMNAALDH1A1KDM4E | |
| SCHEMBL28295570 | 0.81 | SMN1; SMN2 (0.63) | CDC7DBF4LMNAALDH1A1KDM4E | |
| SCHEMBL28295521 | 0.81 | CDC7 (0.57) | CDC7DBF4DHODHLMNAALDH1A1 | |
| SCHEMBL28297285 | 0.81 | CDC7 (0.51) | CDC7DBF4LMNAALDH1A1KDM4E | |
| SCHEMBL28297329 | 0.81 | CDC7 (0.60) | CDC7DBF4LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |