Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CDC7 | O00311 | 1/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297235 | 0.88 | CDC7 (0.59) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL2885708 | 0.88 | TRPM8 (0.78) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL28295659 | 0.87 | CDC7 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL28295521 | 0.87 | CDC7 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL28295523 | 0.87 | CDC7 (0.51) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL28297329 | 0.84 | CDC7 (0.60) | RAB9ANPC1KDM4EMAPTTRPM8 | |
| SCHEMBL28297323 | 0.84 | MEN1 (0.64) | SMN1; SMN2NPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL28297249 | 0.84 | CDC7 (0.53) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL28295554 | 0.83 | RAB9A (0.66) | SMN1; SMN2RAB9ANPC1KDM4EPOLB | |
| SCHEMBL8339292 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |