SCHEMBL28295529

SCHEMBL28295529

CCOC(=O)c1nc(-c2ccc(OC)cc2)oc1C(C)C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 6/20 0.73
PDCD4 Q53EL6 1/20 0.73
IKBKB O14920 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 4/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 3/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
NPBWR1 P48145 1/20 0.47
MAPT P10636 3/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
HTT P42858 1/20 0.46
MAPK10 P53779 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1051765 0.89 TARBP2 (0.71) TARBP2PDCD4IKBKBGAAALDH1A1
SCHEMBL28297291 0.88 TARBP2 (0.57) TARBP2PDCD4IKBKBPOLBALDH1A1
SCHEMBL3535824 0.85 TARBP2 (1.00) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL13771095 0.84 TARBP2 (0.84) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL18003578 0.83 TARBP2 (0.50) TARBP2PDCD4GAAALDH1A1KDM4E
SCHEMBL28297242 0.82 TARBP2 (1.00) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL3539144 0.81 TARBP2 (0.84) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL5192166 0.81 TARBP2 (0.75) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL28873207 0.81 TARBP2 (0.73) TARBP2PDCD4IKBKBPOLBGAA
SCHEMBL3537883 0.81 TARBP2 (0.82) TARBP2PDCD4IKBKBPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed