Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.60 |
| ▸ | CDC7 | O00311 | 8/20 | 0.60 |
| ▸ | DBF4 | Q9UBU7 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.57 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10552788 | 0.89 | TARBP2 (0.57) | PTPN11TRPM8CDC7DBF4MAPT | |
| SCHEMBL2085303 | 0.88 | CDC7 (0.73) | PTPN11TRPM8CDC7DBF4MAPT | |
| SCHEMBL5194957 | 0.87 | GRM6 (0.58) | PTPN11TRPM8CDC7DBF4MAPT | |
| Hydrochloric Acid SCHEMBL11121421 | 0.84 | CDC7 (0.76) | TRPM8CDC7DBF4 | |
| SCHEMBL29660243 | 0.84 | ALOX5 (0.60) | PTPN11TRPM8CDC7DBF4TARBP2 | |
| SCHEMBL4801129 | 0.83 | MAPT (0.78) | TRPM8CDC7DBF4MAPTGAA | |
| SCHEMBL2883597 | 0.83 | PTPN11 (0.69) | PTPN11TRPM8CDC7DBF4MAPT | |
| SCHEMBL13437323 | 0.83 | TARBP2 (0.51) | PTPN11TRPM8CDC7DBF4MAPT | |
| SCHEMBL16039074 | 0.82 | CDC7 (0.76) | PTPN11TRPM8CDC7DBF4MEN1 | |
| SCHEMBL3769955 | 0.82 | PTPN11 (0.58) | PTPN11TRPM8CDC7DBF4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |