Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | CDC7 | O00311 | 2/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.52 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20785682 | 0.91 | TRPM8 (0.63) | ALOX5CDC7DBF4TRPM8RARA | |
| SCHEMBL28295534 | 0.84 | PTPN11 (0.63) | CDC7DBF4TRPM8TARBP2PDCD4 | |
| SCHEMBL22256926 | 0.84 | TARBP2 (0.57) | GABRA2GABRB2DHODHTARBP2PDCD4 | |
| SCHEMBL10552788 | 0.84 | TARBP2 (0.57) | CDC7DBF4TRPM8RARARARB | |
| SCHEMBL16039074 | 0.82 | CDC7 (0.76) | CDC7DBF4TRPM8PTGDR2RARA | |
| SCHEMBL5731955 | 0.82 | TRPM8 (0.50) | ALOX5CDC7DBF4TRPM8RARA | |
| SCHEMBL5194957 | 0.81 | GRM6 (0.58) | CDC7DBF4TRPM8TARBP2PDCD4 | |
| SCHEMBL27761471 | 0.80 | CDC7 (0.69) | CDC7DBF4TRPM8RARARARB | |
| SCHEMBL5909564 | 0.80 | PTGS2 (0.59) | CDC7DBF4PTGDR2RARARARB | |
| SCHEMBL3317668 | 0.79 | ALDH1A1 (0.53) | ALOX5CDC7DBF4TRPM8RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | claimed |