Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 4/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499055 | 0.95 | TARBP2 (0.73) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27189076 | 0.92 | TARBP2 (0.78) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7701292 | 0.88 | TARBP2 (0.67) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29158606 | 0.87 | TARBP2 (0.63) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL16005699 | 0.86 | TARBP2 (0.72) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29158677 | 0.86 | TARBP2 (0.72) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7701068 | 0.85 | ALDH1A1 (0.69) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29158615 | 0.85 | TARBP2 (0.65) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29158666 | 0.85 | TARBP2 (0.54) | TARBP2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29158580 | 0.85 | ALDH1A1 (0.69) | TARBP2KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |