Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888153 | 0.88 | MAPT (0.48) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL20861471 | 0.84 | PPARA (0.53) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL28295550 | 0.84 | PPARA (0.46) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL4077739 | 0.78 | NOTUM (0.38) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL2081784 | 0.74 | MAPT (0.65) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL1045446 | 0.73 | MAPT (0.64) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL12961041 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1RAB9APPARAPPARG | |
| SCHEMBL2517496 | 0.72 | PPARA (0.49) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL13503414 | 0.71 | TARBP2 (0.53) | MAPTALDH1A1LMNARAB9APPARA | |
| SCHEMBL266619 | 0.71 | KDM4E (0.66) | LMNARAB9APPARAPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |