Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890697 | 0.86 | PPARA (0.54) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL8888153 | 0.84 | MAPT (0.48) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL28295573 | 0.84 | MAPT (0.48) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL4484960 | 0.78 | PPARA (0.58) | PPARAPPARGMAPTRAB9AKDM4E | |
| SCHEMBL3530493 | 0.77 | RAB9A (0.53) | PPARAPPARGALDH1A1RAB9AKDM4E | |
| SCHEMBL6958969 | 0.76 | PTGS1 (0.45) | ALDH1A1 | |
| SCHEMBL3532628 | 0.76 | KDM1A (0.57) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL1435871 | 0.75 | ALDH1A1 (0.46) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL4906461 | 0.75 | PPARA (0.52) | PPARAPPARGRAB9AKDM4E | |
| SCHEMBL1436051 | 0.75 | PPARA (0.51) | PPARAPPARGMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |