Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485159 | 0.85 | ALDH1A1 (1.00) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL21303556 | 0.81 | MAPT (0.66) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL29291257 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL13731090 | 0.81 | RAB9A (0.71) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL7976958 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL19343385 | 0.80 | RAB9A (0.81) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL3863062 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL561946 | 0.77 | NR1H4 (0.69) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL6404017 | 0.77 | ALDH1A1 (0.57) | ALDH1A1LMNANOTUMRAB9ANPC1 | |
| SCHEMBL6408207 | 0.77 | ALDH1A1 (0.57) | ALDH1A1LMNANOTUMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-B | miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2023-04-21 | — | — | CN | disclosed |
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |
| CN-106146487-B | Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its preparation method and application | 北京大学 | 2019-05-10 | — | — | CN | disclosed |