SCHEMBL28295624

SCHEMBL28295624

CC(=O)O[SiH2]OC(C)=O.Cc1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
BACE1 P56817 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ESR2 Q92731 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28650304 0.89 BACE1 (0.47) BACE1SMN1; SMN2NPC1ALDH1A1MAPT
Acetic Acid SCHEMBL8166639 0.83 MCL1 (0.53) MCL1PPARGPPARACA12CA1
Biphenyl SCHEMBL8168014 0.83 SMN1; SMN2 (0.50) BACE1SMN1; SMN2ALDH1A1KDM4EMAPT
Bicarbonate SCHEMBL1839338 0.81 MCL1 (0.55) MCL1PPARGPPARACA12CA1
Lithium SCHEMBL30110457 0.79 ESR2 (0.52) MCL1BACE1CA12CA1CA2
Methyl Alcohol SCHEMBL28153974 0.77 ESR2 (0.56) MCL1PPARGPPARABACE1CA12
SCHEMBL616 0.77 ESR2 (0.54) MCL1BACE1CA12CA1CA2
SCHEMBL29706107 0.77 ESR2 (0.54) MCL1BACE1CA12CA1CA2
Methacrylic Acid SCHEMBL29117858 0.77 MCL1 (0.47) MCL1PPARGPPARACA12CA1
SCHEMBL28295641 0.76 ENPP3 (0.44) MCL1PPARGPPARACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-A LED Encapulant composition 日产化学株式会社 2019-05-03 CN disclosed