SCHEMBL28295641

SCHEMBL28295641

CO[SiH2]OC.Cc1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.44
ENPP1 P22413 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 2/20 0.43
NPC1 O15118 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
ESR2 Q92731 1/20 0.42
HTR7 P34969 3/20 0.41
CYP2A6 P11509 2/20 0.41
CYP2B6 P20813 1/20 0.41
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
MCL1 Q07820 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662908 0.87 PTGS2 (0.43) ALDH1A1HPGDHTR7CYP2A6PDCD1
SCHEMBL616 0.84 ESR2 (0.54) ENPP3ENPP1ALDH1A1HPGDNPC1
SCHEMBL29706107 0.84 ESR2 (0.54) ENPP3ENPP1ALDH1A1HPGDNPC1
Biphenyl SCHEMBL4733975 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Water SCHEMBL8948779 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Biphenyl SCHEMBL4603527 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Bromide SCHEMBL1925857 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Iodide SCHEMBL31053161 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Ammonia Solution, Strong SCHEMBL19032131 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1
Hydrochloric Acid SCHEMBL28832617 0.82 ESR2 (0.52) ENPP3ENPP1ALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-A LED Encapulant composition 日产化学株式会社 2019-05-03 CN disclosed