Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839903 | 0.93 | POLB (0.50) | POLBHSD17B10HPGDCYP1A2HDAC1 | |
| SCHEMBL13647141 | 0.93 | POLB (0.50) | POLBHSD17B10HPGDCYP1A2HDAC1 | |
| SCHEMBL9037504 | 0.91 | POLB (0.65) | POLBHSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL9812423 | 0.85 | POLB (0.57) | POLBHSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL29167464 | 0.85 | POLB (0.47) | POLBHSD17B10HDAC1F2RL1AKR1C3 | |
| SCHEMBL21379753 | 0.84 | POLB (0.52) | POLBHSD17B10ALDH1A1HPGDCYP1A2 | |
| SCHEMBL27091485 | 0.84 | POLB (0.48) | POLBHSD17B10HDAC1F2RL1 | |
| SCHEMBL13933865 | 0.83 | F2RL1 (0.49) | POLBHSD17B10HPGDHDAC1F2RL1 | |
| SCHEMBL16294203 | 0.81 | POLB (0.48) | POLBHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL4392427 | 0.80 | NPC1 (0.56) | POLBHSD17B10ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678902-B | Organic catalyst with rigid spiro [ indan-1, 2' -pyrrolidine ] skeleton, ligand, synthesis and application | 北京师范大学 | 2020-05-15 | — | — | CN | disclosed |
| CN-109678902-A | One kind has the organic catalyst, ligand and synthesis and application of rigid spiral shell [indane -1,2 '-pyrrolidines] skeleton | 北京师范大学 | 2019-04-26 | — | — | CN | disclosed |