SCHEMBL28662908

SCHEMBL28662908

CO[SiH2]OC.c1ccc(-c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.43
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAPK1 P28482 1/20 0.42
ABL1 P00519 2/20 0.42
ABCB1 P08183 2/20 0.42
BCR P11274 2/20 0.42
HTR7 P34969 2/20 0.41
MAPT P10636 2/20 0.41
MITF O75030 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
BACE1 P56817 2/20 0.39
LMNA P02545 1/20 0.39
DPP4 P27487 1/20 0.38
ADRB2 P07550 1/20 0.38
PDCD1 Q15116 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8999030 0.87 ALDH1A1 (0.53) ALDH1A1HSD17B10BCL2L1MAPK1MAPT
Biphenyl SCHEMBL63645 0.87 ALDH1A1 (0.53) ALDH1A1HSD17B10BCL2L1MAPK1MAPT
SCHEMBL28295641 0.87 ENPP3 (0.44) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
2-Phenylphenol SCHEMBL27493206 0.85 HPGD (0.68) ALDH1A1HSD17B10HPGDBCL2L1BACE1
Methoxymethane SCHEMBL27842914 0.84 ALDH1A1 (0.50) PTGS2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL21447 0.78 ALDH1A1 (0.61) PTGS2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL2361430 0.78 ALDH1A1 (0.61) PTGS2ALDH1A1HSD17B10HPGDBCL2L1
Benzene SCHEMBL28035419 0.78 ALDH1A1 (0.61) PTGS2ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL27759812 0.75 ALDH1A1 (0.52) PTGS2ALDH1A1HSD17B10HPGDBCL2L1
Methyl Alcohol SCHEMBL27490755 0.75 ALDH1A1 (0.60) PTGS2ALDH1A1HSD17B10HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-B Sealing material composition for LED 日产化学株式会社 2021-11-09 CN disclosed