SCHEMBL28295657

SCHEMBL28295657

CCCc1ccccc1N=C=Nc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
MIF P14174 1/20 0.38
PPARA Q07869 2/20 0.33
PPARG P37231 1/20 0.33
HTR1A P08908 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
CNR2 P34972 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
LIPG Q9Y5X9 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4006078 0.92 CYP3A4 (0.42) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL29516499 0.92 CYP3A4 (0.42) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL10736299 0.85 CYP3A4 (0.53) CYP3A4CYP2D6CYP2C9HTR1AGABRA1
SCHEMBL3820757 0.83 CYP3A4 (0.54) CYP3A4CYP2D6CYP2C9HTR1AGABRA1
SCHEMBL29619878 0.83 CYP3A4 (0.54) CYP3A4CYP2D6CYP2C9HTR1AGABRA1
SCHEMBL31677053 0.80 LIPG (0.51) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL17965857 0.80 LIPG (0.51) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL2766194 0.79 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL93143 0.79 GABRA1 (0.50) CYP3A4CYP2D6CYP2C9PPARAPPARG
SCHEMBL2771239 0.79 GABRA1 (0.48) CYP3A4CYP2D6CYP2C9MIFPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109897351-A A kind of preparation method of hydrolytic-resistant polylactic acid resin 宿迁博古科技有限公司 2019-06-18 CN disclosed