Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741667 | 0.80 | MGAM (0.48) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL28040109 | 0.79 | — | — | |
| SCHEMBL15745840 | 0.79 | MGAM (0.57) | MGAMGAASIMGAM2TRPA1 | |
| SCHEMBL5954824 | 0.78 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27426948 | 0.78 | MGAM (0.41) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL889366 | 0.77 | — | — | |
| SCHEMBL27312535 | 0.76 | MGAM (0.40) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL10001051 | 0.75 | MGAM (0.67) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14022135 | 0.75 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28573654 | 0.74 | ALDH1A1 (0.46) | FAAHTRPA1ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749090-B | The preparation method and applications of 2- (4- hydroxy phenyl) thiazole -4-carboxylic acid ethyl ester's derivative | 淮海工学院 | 2019-05-14 | — | — | CN | disclosed |