⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311876 | 0.83 | ALDH1A1 (0.53) | — | |
| SCHEMBL2706963 | 0.78 | ALDH1A1 (0.48) | — | |
| SCHEMBL197897 | 0.76 | — | — | |
| SCHEMBL6572365 | 0.76 | — | — | |
| SCHEMBL12814201 | 0.76 | — | — | |
| SCHEMBL713608 | 0.76 | — | — | |
| SCHEMBL40361 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL7080078 | 0.75 | — | — | |
| SCHEMBL21715100 | 0.74 | — | — | |
| SCHEMBL5171320 | 0.74 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260199-A | Benzimidazole pyrazine-3-carboxamide compound and preparation method and application thereof | 中山大学 | 2022-11-01 | — | — | CN | claimed |
| US-20250092050-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | SUN YAT-SEN UNIVERSITY (CN) | 2025-03-20 | — | — | US | disclosed |
| EP-4461733-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | Sun Yat-Sen University (CN) | 2024-11-13 | — | — | EP | disclosed |
| CN-117164418-B | Alpha-halogenated ketone, efficient synthesis method and application thereof | 徐州医科大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-115260199-B | Benzimidazole-pyrazine-3-carboxamide compound and preparation method and application thereof | 中山大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-117164418-A | Alpha-halogenated ketone, efficient synthesis method and application thereof | 徐州医科大学 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023165165-A1 | BENZOIMIDAZOPYRAZINE-3-CARBOXAMIDE COMPOUND TARGETING A2A AND ANTI-TUMOR IMMUNOLOGICAL FUNCTION THEREOF | 中山大学 | 2023-09-07 | — | — | WO | disclosed |
| CN-114539265-B | A2A-targeting benzimidazolopyrazine-3-carboxamides and their tumour immune function | 中山大学 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023130701-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | 中山大学 | 2023-07-13 | — | — | WO | disclosed |
| CN-114276354-B | 1-aminobenzo [4,5] imidazo [1,2-a ] pyrazine-3-carboxamide compound, preparation and application thereof | 中山大学 | 2023-06-02 | — | — | CN | disclosed |
| US-20120039848-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2012-02-16 | — | — | US | disclosed |
| US-20110300104-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110250172-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-10-13 | — | — | US | disclosed |
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-08-04 | — | — | US | disclosed |
| US-20110142798-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110064698-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-03-17 | — | — | US | disclosed |
| US-7534887-B2 | Thiazoline derivative and use of the same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20070010528-A1 | Thiazoline derivative and use of the same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1669352-A1 | THIAZOLINE DERIVATIVE AND USE OF THE SAME | Takeda Pharmaceutical Company Limited (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0178775-A2 | Fluorescent indicator dyes for calcium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-04-23 | — | — | EP | disclosed |