Methacrylic Acid

Methacrylic Acid

SCHEMBL28295764

C=C(C)C(=O)O.CCNCC(=O)O

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.37
FFAR3 O14843 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
EGLN1 Q9GZT9 3/20 0.33
LMNA P02545 2/20 0.33
SLC15A2 Q16348 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TGFBR1 P36897 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
AKR1B1 P15121 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28462494 0.88 CTH (0.41) CTHFFAR3HDAC3HDAC1HDAC2
Methacrylic Acid SCHEMBL5514685 0.85 TP53 (0.44) FFAR3ALDH1A1TGFBR1ALOX15HSD17B10
Formaldehyde SCHEMBL21638861 0.85
Oxalic Acid SCHEMBL1421278 0.85 FFAR3 (0.41) CTHFFAR3HDAC3HDAC1HDAC2
Acetic Acid SCHEMBL2851414 0.85 CTH (0.42) CTHFFAR3HDAC3HDAC1HDAC2
Acetic Acid SCHEMBL27602622 0.85 CTH (0.42) CTHFFAR3HDAC3HDAC1HDAC2
SCHEMBL41068 0.85
Methacrylic Acid SCHEMBL19181034 0.83 TP53 (0.42) FFAR3ALDH1A1TGFBR1ALOX15HSD17B10
Methacrylic Acid SCHEMBL9139201 0.83 TP53 (0.42) FFAR3ALDH1A1TGFBR1ALOX15HSD17B10
Methacrylic Acid SCHEMBL19181035 0.83 TP53 (0.42) FFAR3ALDH1A1TGFBR1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689609-A Dicarboxylic acid crystallizates and its manufacturing method 花王株式会社 2019-04-26 CN disclosed