SCHEMBL28295781

SCHEMBL28295781

C=C[SiH2]C(=O)c1ccccc1OC(C)C

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.57
KCNK3 O14649 4/20 0.47
KCNK9 Q9NPC2 4/20 0.47
ALDH1A1 P00352 3/20 0.43
ACHE P22303 1/20 0.43
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
RXFP1 Q9HBX9 2/20 0.43
MRGPRX1 Q96LB2 1/20 0.41
BRPF1 P55201 2/20 0.41
PRMT5 O14744 1/20 0.40
HTR2A P28223 1/20 0.40
TSPO P30536 1/20 0.40
GPR183 P32249 1/20 0.40
APLNR P35414 1/20 0.40
PNLIP P16233 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293895 0.82 CTSD (0.53) KCNK3KCNK9ALDH1A1RXFP1
SCHEMBL2094687 0.76 IRAK4 (0.68) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28293903 0.76 IRAK4 (0.58) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28957480 0.76 IRAK4 (0.58) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL2094692 0.76 IRAK4 (0.72) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL7088362 0.76 IRAK4 (0.72) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28293902 0.74 IRAK4 (0.70) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL104892 0.74 IRAK4 (0.70) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28295793 0.74 IRAK4 (0.55) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL19531891 0.73 IRAK4 (0.64) IRAK4KCNK3KCNK9ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790190-A Curing agent for silicone rubber material 硝基化学阿绍有限公司 2019-05-21 CN claimed