Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518741 | 0.78 | — | — | |
| SCHEMBL3717170 | 0.78 | — | — | |
| Pyrazole SCHEMBL28114392 | 0.74 | SCN4A (0.37) | — | |
| Isoquinoline SCHEMBL1133594 | 0.73 | MAPT (0.38) | CYP1A2 | |
| Imidazole SCHEMBL28295853 | 0.72 | ALDH1A1 (0.54) | LOXL2NUDT1 | |
| Pyrazole SCHEMBL16874402 | 0.72 | — | — | |
| Pyrazole SCHEMBL30626480 | 0.71 | — | — | |
| Pyrazole SCHEMBL30854861 | 0.71 | — | — | |
| Pyrazole SCHEMBL5664483 | 0.71 | — | — | |
| Pyrazole SCHEMBL1384 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232600-B | Indolin-2-one and 1,3- dihydro-pyrrole simultaneously [3,2-c] pyridin-2-ones derivative | 豪夫迈·罗氏有限公司 | 2019-05-14 | — | — | CN | disclosed |