Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631357 | 0.82 | RAD52 (0.44) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL27573204 | 0.81 | RAD52 (0.43) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL24451794 | 0.80 | HTR2C (0.45) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL22542020 | 0.78 | ADRB1 (0.52) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL22542046 | 0.78 | ADRB1 (0.52) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL4025392 | 0.78 | ADRB1 (0.52) | RAD52SLC6A4SLC6A3SLC6A2HTR2C | |
| SCHEMBL22801996 | 0.77 | MAPT (0.46) | RAD52HTR2CGSK3B | |
| SCHEMBL22801980 | 0.77 | MAPT (0.46) | RAD52HTR2CGSK3B | |
| SCHEMBL1473008 | 0.77 | USP2 (0.49) | RAD52CA2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL28596325 | 0.77 | USP2 (0.49) | RAD52CA2SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |